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Dietary fiber content in clinical ketogenic diets modifies the gut microbiome and seizure resistance in mice.

Özcan E, Yu KB, Dinh L, Lum GR, Lau K, Hsu J, Arino M, Paramo J, Lopez-Romero A, Hsiao EY.

Nat Commun. 2025 Jan 24;16(1):987. PMCID: PMC11759687


Murine maternal microbiome modifies adverse effects of protein undernutrition on offspring neurobehaviour

Coley-O'Rourke EJ, Lum GR, Pronovost GN, Yu LW, Özcan E, Yu KB, McDermott J, Chakhoyan A, Goldman E, Vuong HE, Paramo J, McCune S, Sejane K, Renwick S, Bode L, Chu A, Calkins KL, Hsiao EY.

Nat Microbiol. 2025 Jul;10(7):1648-1664. PMID: 40514563


Complex carbohydrate utilization by gut bacteria modulates host food consumption

Yu KB, Son C, Özcan E, Chandra A, Paramo J, Varghese A, Roice A, Finnigan D, Chandra F, Novoselov A, Kazmi SA, Lum GR, Lopez-Romero A, Lynch JB, Hsiao EY.

Nat Commun. 2025 Sep 25;16(1):8408. PMCID: PMC12462444.


The microbial metabolite imidazole propionate modulates hypothalamic activity and stress-induced behaviors

Agirman G, Quicho MNB, Connelley KK, Zhang X, Lynch JB, Ha SM, Schmidt HM, Özcan E, Liang AX, Yu KB, Ahn IS, Qian C, Paramo J, Zhang S, Espinoza A, Turnbaugh PJ, de Aguiar Vallim TQ, Yang X, Church A, Hsiao EY.

Cell Host Microbe. 2025 Dec 10;33(12):2030-2042.e9. PMCID: PMC12811846

Bifidobacterium longum subsp. infantis utilizes human milk urea to recycle nitrogen within the infant gut microbiome

You X, Rani A, Özcan E, Lyu Y, Sela DA

Gut Microbes 15 (1), 2192546. PMCID: PMC10054289


Bifidobacterium infantis utilizes N-acetylglucosamine-containing human milk oligosaccharides as a nitrogen source

Li S, You X, Rani A, Özcan E, Sela DA.

Gut Microbes. 2023 Dec;15(2):2244721. PMCID: PMC10448974

Are changes in the gut microbiome a contributor or consequence of autism—why not both?.

Özcan E, Hsiao EY

Cell Rep Med.2022 Jan 18;3(1):100505. PMCID: PMC8784764.


Interactions between the gut microbiome and ketogenic diet in refractory epilepsy

Özcan E, Lum GR, Hsiao EY.

Int Rev Neurobiol. 2022;167:217-249. PMID: 36427956


In vitro Models of Host–Microbial Interactions Within the Gastrointestinal Tract

Özcan E, Levantovsky R, Sela DA

In Functional Foods and Beverages: In vitro Assessment of Nutritional, Sensory, and Safety Properties. N. Bordenave and M. G. Ferruzzi Eds, John Wiley & Sons, Oxford, UK.


Inefficient Metabolism of the Human Milk Oligosaccharides Lacto-N-tetraose and Lacto-N-neotetraose Shifts Bifidobacterium longum subsp. infantis Physiology Physiology

Özcan E, Sela DA

Front Nutr. 2018;5:46. PubMed Central PMCID: PMC5989456

A human gut commensal ferments cranberry carbohydrates to produce formate

Özcan E, Sun J, Rowley DC, Sela DA

Appl and Environ Microbiol. 83:e01097-17. PMID: 28667113 PMCID: PMC5561279

Characterization of chemical, biological, and antiproliferative properties of fermented black carrot juice, shalgam

Ekinci FY, Baser GM, Özcan E, Güçlü-Üstündağ Ö, Korachi M, Sofu A, Chen C-Y O, Blumberg JB

European Food Research and Technology. 242, 1355–1368.


Black tea processing waste as a source of antioxidant and antimicrobial phenolic compounds

Güçlü-Üstündağ Ö, Erşan S, Özcan E, Özan G, Kayra N, Ekinci FY

European Food Research and Technology. 242, 1523–1532


Mechanism Underlying the Effects of Lactic Acid Bacteria (LAB) on Phenolic Compounds

Özcan E and Ekinci FY

International Journal of Food and Biosystems Engineering, 1(1), 7-15

Glycan cross-feeding activities between bifidobacteria under in vitro conditions conditions

Turroni F, Özcan E, Milani C, Mancabelli L, Viappiani A, van Sinderen D, Sela DA, and Ventura M

Front in Microbiol. 6: 1030. PMCID: PMC4585166

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