Separation Of Inositols From Sugars And Sugar Alcohols

William Baumgartner, Saska, Michael  |  7/9/2007 11:16:33 PM

Saska, Michael; Diack, Moustapha
Date Posted: 11/15/2000
Patent Status: issued
Patent Number: 5,482,631

When a strong base anion exchange resin, such as a chloride-form strong base anion exchange resin, is conditioned with a low concentration of hydroxyl (for example, an NaOH solution with a concentration between 1 and 10 mM), the conditioned resin separates in, sit, Is from sugars and sugar alcohols, while still allowing ready desorption of the sugars from the resin. The feedstock is first passed over a column containing this conditioned resin, followed by a mobile phase solvent, preferably water. The inositols have a lower affinity for the treated resin than do the sugars and sugar alcohols in the feedstock, and therefore pass through the column more quickly. The process may economically be performed on industrial-scale inositol separations, particularly when used in a preferred simulated moving bed chromatographic system.

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