Veterinary Medicine
 more...>Current Patents>Veterinary Medicine>

Attenuated, Invasive Vaccines Against Fish Pathogens

Thune, Ronald L.; Cooper, Richard K.
Date Posted: 11/15/2000
Patent Status: issued
Patent Number: 6,010,705

Abstract:
Live-attenuated vaccines against Edwardsiella ictaluri or against Pasteurella piscicida are disclosed. Both vaccines are incapable of reversion to virulence, because both are made by deletion mutations in the aroA gene, the purA gene, or both. These vaccines may be used not only to vaccinate fish against Edwardsiella ictaluri or Pasteurella piscicida, but also to serve as vectors to present antigens from other pathogens to the fish, thereby serving as vaccines against other pathogens as well, with no risk of infection by reversion to the virulent form of the pathogen in which the antigen occurs naturally.

Last Updated: 3/17/2014 2:38:47 PM

Have a question or comment about the information on this page?
Click here to contact us.