Robert Carver | 11/29/2006 11:14:22 PM
ACCESSION NO: 0208913 SUBFILE: CRIS
PROJ NO: LAB93825 AGENCY: CSREES LA.B
PROJ TYPE: HATCH PROJ STATUS: NEW
START: 01 OCT 2006 TERM: 30 SEP 2011
INVESTIGATOR: Chen, Z.
PLANT PATHOLOGY & CROP PHYSIOL
LOUISIANA STATE UNIVERSITY
BATON ROUGE, LOUISIANA 70893
Investigating Maize-Aspergillus Flavus Interaction for Enhancement of Resistance to Aflatoxin Contamination
NON-TECHNICAL SUMMARY: Aflatoxins, the toxic and highly carcinogenic secondary metabolites of A. flavus and A. parasiticus, are produced during infection of susceptible crops, such as maize, especially under hot and dry weather conditions. Aflatoxin contamination in food and feed not only causes millions of dollars in losses to U. S. farmers, but also poses serious health hazards to humans and domestic animals. Severe aflatoxin outbreaks occurred in Louisiana, other Southern states, and the Midwest Corn Belt in the past when there was a prolonged drought, such as the ones occurred in 1987 and 1998. The purpose of the present proposal is to enhance maize resistance to A. flavus infection/aflatoxin production through understanding of host-fungus interactions. Understanding these interactions and the host resistance mechanisms may enable us to develop commercial varieties that are resistant to A. flavus infection and aflatoxin contamination, which will not only reduce the economic losses to farmers, but also ensure food and feed safety.
The long-term objective of this proposed study is to enhance aflatoxin resistance in maize through either genetic engineering or marker-assisted breeding.
Name: Chen, Z. Y.